You can segment your email lists based on demographic data such as city, state, zip etc or any other subscriber property.
This type of segmentation is done using the Advanced search utility.
With this utility you can create a new list segment, a campaign filter or export the search results to a spreadsheet.
Tracking-based list segmentation
Tracking based on campaign clicks or views or the absence of them.
With an easy to use menu you can create new lists for subscribers who opened (or not), clicked (or not) in a previous campaign.
Example: you want a list with subscribers who clicked a specific link in a campaign or did not open the campaign at all etc.
This concept is similar to follow-up campaigns but you create only a filter and not a campaign. You can do it by going to your summary report.
Then most likely you will want to use this filter in a new campaign with other parameters.
Segmentation using triggers
Using triggers you can do the following (among else):
Update a subscriber field value. You create a custom subscriber field, let's say #tag1. Then you put a trigger to update this field's data upon click or view.
Add and/or remove the subscriber to other lists.
Benefits of list segmentation
Segmentation is key to email marketing success. It increases engagement.
You can create and use filters in your campaigns to focus only to subscribers that fit the filter criterion.
When using filters your original mailing lists remain intact. You only focus to a sub-group of the mailing list.
List segmentation leads to more relevant and targeted email campaigns.